30/07/2024

Things you had no idea are contagious

From laughter to loneliness

When something is contagious, it means it’s transmissible and it can spread from one person to another. We often associate this with diseases, but many other things can be—and indeed are—contagious. We’re talking about sensations, emotional states, behaviors, and actions.

In this gallery, we bring you a number of things you may not know are contagious:
  • Feeling cold - Temperature contagion is a thing. Research conducted at the University of Sussex in the UK found that just looking at someone who is cold will make our own body temperature drop.
  • Loneliness - A large-scale study, which considered data for more than 60 years, found that lonely people often share their loneliness with other people. These people, in turn, start to feel lonely as well.
  • Laughter - Laughing is definitely contagious. According to psychologist Robert Provine, “you're 30 times more likely to laugh with other people than you are on your own.”
  • Yawning - Raise your hand if you yawn when you see someone else doing it! This behavior can even occur when we hear, or even read, about someone yawning.
  • Noncommunicable diseases - Noncommunicable diseases (NCDs) are conditions that are usually not caused by an acute infection and that can't be transmitted between people. NCDs are believed to be caused by a mix of genetics, environmental factors, and lifestyle choices. Examples include heart disease, diabetes, cancer, and obesity.
  • Restaurant orders - A study conducted by the University of Illinois found that diners tend to order foods that are similar to those of their companions. “Diners wanted to be different from their dining companions, but not too different."
  • Divorce - A 2013 study found that people who were friends with divorcees were 75% more likely to get a divorce than those whose friends were still married.
  • Goals - Another person's behavior, especially in our inner circles, can affect ours. How many times has someone left a party early and you found yourself looking at the watch, too? The same applies with goals.
  • Happiness - Many of us have experienced this when we are around positive, upbeat people, right? It turns out, this positive influence spreads even further around us. “Even people we don’t know and have never met have a bigger effect on our mood than substantial increases in income.”
  • Cancer - Cancer is a noncommunicable disease, but there are animals that can actually spread cancer to each other, namely Tasmanian devils, soft-shelled clams, and dogs. While the transmission of cancerous cells between humans is not believed to occur under the same circumstances, there are cases where this is believed to have occurred.
  • Itching - It’s safe to say that most of us have felt our own skin tingling after we’ve seen someone scratch an itch. This happens all the time, and it’s not only limited to humans. Experiments with rats have reached similar conclusions.
  • Bad behavior - A theory known as the broken windows theory suggests that signs of crime, anti-social behavior, and civil disorder trigger more of the same behavior, thus spreading it.
  • High blood pressure - Researchers found that mice infected with cytomegalovirus (CMV) developed higher blood pressure than those without the virus. CMV altered their behavior and caused them to eat more high-cholesterol foods. And, it turns out, trials with human cell cultures had similar results.
  • Desire for new things - We tend to rate objects as more valuable when other people want them. Though the “wedding-band syndrome,” as psychologist Elizabeth Lombardo calls it, is also applicable to people. “A man is more attractive if someone already wants him—he must be worth having,” she explained.
  • Stomach ulcers - Stomach ulcers are mainly caused by a bacterium called Helicobacter pylori, which is carried by a large percentage of the world’s population. While many people don’t experience any symptoms, others may develop peptic ulcers in the stomach and small intestine.
  • Stress - When we detect signs of stress in other people, our bodies release stress hormones. And this doesn’t even need to occur in person. This stress response can be triggered by an email, a text, or social media, for example.
  • Negative thinking - According to a study by the University of Notre Dame, you can “catch” negative thinking if exposed to it. The study randomly paired freshmen with roommates who were highly prone to brooding. The freshmen “caught” their negative-thinking style after three months.
  • Cavities - Kissing someone with poor dental hygiene may not be good for your oral health. This is because cavity-causing bacteria may end up in your mouth.

28/07/2024

Founding of Singapore 1819


Sir Thomas Stamford Raffles and the Foundation of Singapore

Two hundred years ago, an important treaty was negotiated by the Englishman Sir Thomas Stamford Raffles, leading to the establishment of the British colony of Singapore. The foundation of modern Singapore and the actions of the British Empire marked a new chapter for this southern Asian island which grew into a commercial and cosmopolitan hub, largely due to its ideal location as a trading port.

Before the expansion of European imperial ambitions into Asia, Singapore had been known as “Pu-luo-chung”, as recorded by some early third century Chinese accounts. As a settlement it grew alongside trade and was known as Temasek which loosely translates as “Sea Town”. It would later be renamed Singapura, or the “Lion City” abbreviated from the Sanskrit words which according to legend, were derived from a Prince who had spotted an animal he had never come across before whilst on a hunt.

For this small Asian island, its location at the southern tip of the Malay Peninsula would make it a prime trading spot, on the confluence of many trading routes for vessels travelling from all across the ancient world, part of the wider connections known as the Silk Roads. The island would for centuries come under the control of foreign powers vying for hegemony in the region including the Srivijaya Empire based in Sumatra, Indonesia, whilst in the twelfth century the Majapahit Empire from the island of Java and later the Siamese would use it as a vassal state. By the fifteenth century Malacca was exercising dominance until European powers intervened and Portugal enhanced its imperial portfolio.


Founding of Modern Singapore
This statue of Stamford Raffles has since been moved to a spot along the Singapore River where the British were believed to have landed in 1819. (c. 1905. Image from the National Museum of Singapore)

Sitting on the tip of the Malay Peninsula where sea routes intersect, the island of Singapore had long impressed mariners, traders and rulers for its strategic location, good rivers and great potential.2 The British were similarly enamoured by Singapore some centuries later. Under their charge in the 19th and 20th centuries, the ancient port was revived, attracting a melting pot of immigrants who together with founder Stamford Raffles, and British residents of Singapore William Farquhar and John Crawfurd, helped build a thriving emporium and shape the city we know today.

In 1818, the Dutch set up a military post in Riau with the support of the Johor Sultanate. This move gave them control of a critical trading passage through the Strait of Malacca. It also gave them the liberty to impose heavy taxes on British ships at their ports. The Dutch stratagem was effective in persuading the British to relinquish control of the region, however Englishman Stamford Raffles was keen to protect British commercial interests. To this end, he embarked on a mission to hunt down a new trading base near the Malay Peninsula for the British East India Company.

In January 1819, a fleet of eight ships led by Raffles explored the possibility of hoisting the British flag on Indonesia’s Karimun islands. The islands however, proved to be too rocky. On the recommendation of hydrographer Daniel Ross, who was in charge of the party's survey ships, they made their way to Singapore.7 The island passed muster. It lay along the British trade route towards the Straits of China and boasted a natural sheltered harbour by the mouth of the Singapore River. With the notable absence of the Dutch, Raffles acted quickly to establish a trading post.


History of Singapore
Thomas Stamford Raffles, detail of an oil painting by G.F. Joseph in 1817

In January 1819 Stamford Raffles of the English East India Company, searching for a trading site, forestalled by the Dutch at Riau, and finding the Carimon (Karimun) Islands unsuitable, landed at Singapore. He found only a few Chinese planters, some Indigenous people, and a few Malays and was told by the hereditary chief, the temenggong (direct ancestor of the sultans of present-day Johor, Malaysia), that the company could purchase land. The temenggong, however, was a subordinate of his cousin Abdul Rahman, sultan of Riau-Johor, who was under Dutch surveillance. Furthermore, Abdul Rahman was a younger son and not a sultan de jure. Raffles, disobeying instructions not to offend the Dutch, withdrew his own recognition of Abdul Rahman’s suzerainty over Singapore and installed Abdul Rahman’s elder brother, Hussein (Husain), to validate the purchase of land there on behalf of the company. The Dutch protested. In London the company’s court of directors, though it decided that Raffles had contravened instructions, took no action.

In 1824 an Anglo-Dutch treaty left Malaya and Singapore in the British sphere, and in August the whole of Singapore Island was ceded to the British for a monetary payment. Two years later Singapore, Penang, and Malacca (Melaka) were combined as the Straits Settlements to form an outlying residency of India. In 1830 they were reduced to a residency under Bengal, and two years later Singapore became their capital. When the East India Company lost its monopoly of the China trade (1833), it also lost its interest in Malaya. The settlements were transferred to the direct control of the governor-general of India in 1851. In 1867 they were made a crown colony under the Colonial Office in London.

Meanwhile, Singapore’s trade had suffered after 1842 from British development of a rival port, Hong Kong, as later it was to suffer from the French occupation of mainland Southeast Asia and the development of Saigon (now Ho Chi Minh City) and Haiphong in Vietnam and from the establishment of Dutch ports and shipping lines in the Dutch East Indies (present-day Indonesia). With the opening of the Suez Canal in 1869 and the advent of steamships, however, an era of prosperity began that led eventually to the construction of 3 miles (5 km) of wharves at Tanjong Pagar and finally, in 1921, a naval base. The economic growth of the Malay states after they became British protectorates enlarged transit trade.


Founding years of modern Singapore

The establishment of a British trading post in Singapore in 1819 by Sir Stamford Raffles led to its founding as a British colony in 1824. This event has generally been understood to mark the founding of colonial Singapore, a break from its status as a port in ancient times during the Srivijaya and Majapahit eras, and later, as part of the Sultanate of Malacca and the Johor Sultanate.

A significant port and settlement, known as Temasek, later renamed Singapura, existed on the island of Singapore in the 14th century. Vietnamese records indicate possible diplomatic relationship between Temasek and Vietnam in the 13th century and Chinese documents describe settlements there in the 14th century. It was likely a vassal state of both the Majapahit Empire and the Siamese at different times in the 14th century. Around the end of the 14th century, its ruler Parameswara was attacked by either the Majapahit or the Siamese, forcing him to move on to Melaka where he founded the Sultanate of Malacca, Archaeological evidence suggests that the main settlement on present-day Fort Canning was abandoned around this time, although a small-scale trading settlement continued in Singapore for some time afterwards. Between the 16th and 19th centuries, the Malay archipelago was gradually taken over by the European colonial powers, beginning with the Portuguese conquest of the Malacca Sultanate in 1511. In 1613, the Portuguese burnt down a trading settlement at the mouth of the Singapore River, after which Singapore lapsed into insignificance in the history of the region for two hundred years.

The early dominance of the Portuguese was challenged during the 17th century by the Dutch, who came to control most of the region's ports. The Dutch established a monopoly over trade within the archipelago, particularly in spices, then the region's most important product. Other colonial powers, including the British, were limited to a relatively minor presence in that period.Singapore's name comes from 'Singa Pura' which means Lion City in Sanskrit. According to the Sejarah Melayu (Malay Annals), a Sumatran prince called Sang Nila Utama landed on Temasek[8] (Singapore's old name) and saw a Lion which is called 'Singa' in Malay. Thus he gave the island a new name, 'Singapura'.


Stamford Raffles
Portrait of Stamford Raffles by George Francis Joseph 1817

Sir Thomas Stamford Bingley Raffles FRS FRAS (5 July 1781 – 5 July 1826) was a British colonial official who served as the governor of the Dutch East Indies between 1811 and 1816 and lieutenant-governor of Bencoolen between 1818 and 1824. Raffles was involved in the capture of the Indonesian island of Java from the Dutch during the Napoleonic Wars. It was returned under the Anglo–Dutch Treaty of 1814. He also wrote The History of Java in 1817, describing the history of the island from ancient times. Rafflesia flower was named after him.

Raffles also played a role in further establishing the British Empire's reach in East and Southeast Asia. He secured control over the strategically located Singapore from local rulers in 1819 to secure British access along the Strait of Singapore and the nearby seas in the region, particularly the Indian Ocean and the South China Sea. His actions were initially not endorsed by the British government and led to tensions between the British and the Dutch; war was avoided under the Anglo–Dutch Treaty of 1824 which firmly established their spheres of influence, whereby the Dutch would relinquish its claims to Singapore and the British seceding Bencoolen in Sumatra to the Dutch. An entrepôt was subsequently established in Singapore for maritime trade between Europe and Asia.

While Raffles was largely credited for the founding of contemporary Singapore, the early running of day-to-day operations was mostly done by William Farquhar, who served as the first Resident of Singapore from 1819 to 1823. Raffles soon returned to England in 1824, where he died on his birthday in 1826 at the age of 45. His legacy while complex remains significant in Singapore, most notably the Raffles's Landing Site, as well as his name being a common sight in numerous entities and institutions throughout the country. Others have argued against excessive reverence as he was an imperialist who projected colonialism onto the population of Singapore that predated his arrival.


Temasek
Part of Mao Kun map from Wubei Zhi which is based on the early 15th century navigation maps of Zheng He showing Temasek (淡馬錫) at the top left

Temasek (also spelt Temasik) is an early recorded name of a settlement on the site of modern Singapore. The name appears in early Malay and Javanese literature, and it is also recorded in Yuan and Ming Chinese documents as Danmaxi (Chinese: 單馬錫; pinyin: Dānmǎxī; Pe̍h-ōe-jī: Tan-má-sek or Chinese: 淡馬錫; pinyin: Dànmǎxī; Pe̍h-ōe-jī: Tām-má-sek). Two distinct settlements were recorded in Temasek – Long Ya Men (Malay: Batu Berlayar) and Ban Zu (Malay: Pancur). The name is used in modern-day Singapore for national honours as well as institutions and corporations.

While the early history of Singapore is obscured by myth and legend, some conclusions can be drawn from archaeological evidence and from written references by travellers. Archaeology points to an urbanised settlement on the site by the 14th century. At its height, the city boasted a large earthen city wall and moat; many of the buildings were built with stone and brick foundations. Remains of old pottery, coins, jewellery and other artefacts have been found, with many of these artefacts believed to be imported from various parts of China, India, Sri Lanka, and Indonesia. These are sometimes seen as evidence of the city's status as a regional trade centre. An aquatic route, part of the larger Silk route, passed through Temasek.

From the 7th to the 11th centuries, the island of Singapore was controlled by the Srivijaya empire based in Sumatra. Diplomatic relationships between Temasek and Vietnam may have begun in the 13th century. Temasek was a fortified city and trading centre in the 14th century. It was recorded that during the Yuan dynasty, envoys were sent to Long Ya Men (Dragon's Teeth Gate, thought to be the entrance of Keppel Harbour) in 1320 to obtain tame elephants. The people of Long Ya Men then returned in 1325 with a tribute and trade mission to China.[6] In around 1330, the Chinese traveller Wang Dayuan visited the island and mentioned two distinct settlements in Temasek: Long Ya Men and Ban Zu (a transcription of the Malay name pancur meaning a "spring").[7] In his work Daoyi Zhilüe, Wang described Long Ya Men as the two hills of Temasek that looked like "Dragon's teeth" between which a strait runs


Sang Nila Utama
Statue of Sang Nila Utama at the Raffles' Landing Site as part of events commemorating the bicentennial of the founding of modern Singapore, along with other pioneers of the modern period of Singapore

According to the Malay Annals, the emporium of Singapore was founded in 1299 by Sang Nila Utama. While hunting on Bintan, he spotted a stag and started chasing it up a small hill but, when he reached the top, the stag vanished. He then came to a very large rock and decided to climb it. When he stood on top of the rock, he looked across the sea and saw another island with a white sandy beach which had the appearance of a white sheet of cloth. Asking his chief minister what island it was, he was told that it was the island of Temasek now known as Singapore. While his ship was out at sea, a great storm erupted and the ship was tossed about in the huge waves and began to take in water. To prevent it from sinking, his men threw all the heavy things on board into the sea to lighten the ship. But still water kept entering the ship. On the advice of the ship's captain, he threw his crown overboard as a gift to the sea. At once, the storm died down and he reached Temasek safely.

He landed safely on the beach and went to hunt wild animals near the river mouth on a patch of open ground, now referred to as the Padang. Suddenly, he saw a strange animal with a red body, black head and a white breast, which swiftly disappeared into the jungle. Impressed by this beast's beauty, he asked his chief minister Demang Lebar Daun what animal it was and was informed that it was a lion. Pleased with this as he believed it to be a good omen, he decided to build his new city in Temasek. He and his men stayed on the island and founded a city, renaming the island to Singapura, which in Sanskrit means "Lion City".

Sang Nila Utama fathered two sons with Wan Sri Bini, born Raja Kechil-Besar and Raja Kechil-Muda the elder son was married to Nila Panchadi, a princess from India and the younger was married to his cousin, a granddaughter of Demang Lebar Dawn. After ruling Singapura for 48 years, Sang Nila Utama died in 1347 and Raja Kechil-Besar ascended to the throne as Sri Wikrama Wira, becoming the second Raja of Singapura; Kechil-Muda was appointed his prime minister and Bendahara of its port. Sang Nila Utama was buried on Bukit Larangan, now known as Fort Canning Hill; the exact location of his grave is unknown, although the altar at Keramat Iskandar Shah may share a site with the royal burials atop the hill.


Parameswara of Malacca
A depiction of Parameswara, born 1344 & died 1414 (aged 70)

Parameswara (1344 – c. 1414), thought to be the same person named in the Malay Annals as Iskandar Shah, was the last king of Singapura and the founder of Malacca. According to the Malay Annals, he ruled Singapura from 1389 to 1398. The king fled the island kingdom after a Majapahit naval invasion in 1398 and founded his new stronghold on the mouth of Bertam river in 1402. Within decades, the new city grew rapidly to become the capital of the Malacca Sultanate. Portuguese accounts however, written a hundred years after his death, suggest he was from Palembang in Sumatra and usurped the throne of Singapura; he was driven out, either by the Siamese or the Majapahit, and went on to found Malacca.

he name Parameswara is found in Portuguese sources such as Suma Oriental, and written Paramicura or Parimicura. Parameswara is a Hindu name derived from the Sanskrit word Parameśvara (Sanskrit: परमेश्वर), a concept literally meaning the "Supreme Lord". The word "parama" meaning "the supreme" is added to Ishvara as an intensifier. Parameśvara is also one of the names of Lord Shiva. However, the name Parameswara is not found in the Malay Annals, which tell a romanticized history of the kingdoms of Singapura and Malacca. It gives the name Iskandar Shah as the last ruler of Singapura and founder of Malacca. Iskandar is Persian for "Alexander", after Alexander the Great, and Shah the Persian title for a king. It has been conjectured that Iskandar Shah of the Malay Annals is the same person as Parameswara based on certain commonalities in their biographies.

The Ming Chronicle (Ming Shilu) recorded that the consort of Parameswara known as Bā-ér-mí-sū-lǐ (八兒迷蘇里) ('Parameswari') attended a banquet together with the king Bai-li-mi-su-la (拜里迷蘇剌, 'Parameswara') in the Ming court.[5] It is more likely that 'Parameswari' ("Supreme Lordess") referred to a title rather than a given name as evidenced by its application in the Malay Annals to Sang Nila Utama's mother-in-law, Queen Parameswari Iskandar Shah, and is in fact still in use today in the form of "Permaisuri" ('Queen') in the Malay language. Therefore, the name Parameswara is also believed to be a small part of a longer regnal title which was something common among Malay royals until the present day. Apart from Parameswara the founder of Malacca, Abu Syahid Shah, the fourth Sultan of Malacca, was also titled "Raja Sri Parameswara Dewa Shah".


Raffles's Landing Site
The office towers at Raffles Place on the south bank of the Singapore River serve as a backdrop against Sir Stamford Raffles's statue located at Raffles' Landing Site on the river's opposite bank

Raffles's Landing Site is the location where tradition holds that Sir Stamford Raffles landed in on 28 January 1819. The site is located at Boat Quay within the Civic District, in the Downtown Core of the Central Area, Singapore's central business district.

On 28 January 1819, Sir Stamford Raffles landed at this site for his first visit, which lasted ten days. During this period, with the help of Major William Farquhar, he concluded the first treaty with the local rulers Temenggong Abdul Rahman and Sultan Hussein Shah. The site is denoted by a statue of Sir Stamford Raffles and is located on the north bank of the Singapore River. The present polymarble statue was unveiled in 1972 which was made from plaster casts from the original 1887 figure that currently stands opposite Victoria Concert Halls.

In 2019, as part of events commemorating the bicentennial of the Founding of modern Singapore, numerous alterations have been made to and around the statue of Raffles such as using camouflage to make the statue 'disappear' into the backdrop of the buildings in Raffles Place on the south bank,[2] and erecting statues of Raffles's contemporaries such as Munshi Abdullah, Tan Tock Seng, and Naraina Pillai along with that of the founder of the Kingdom of Singapura, Sang Nila Utama.


First Landing in Singapore 200 years ago on 28 Jan 1819
Plaque on the plinth of the statue of Sir Stamford Raffles at Raffles’ Landing Site by the Singapore River

Two hundred years ago, Sir Thomas Stamford Raffles negotiated an important treaty, leading to the establishment of the British colony of Singapore. Raffles Hotel in Singapore, named after him, is one of the most famous hotels in the world.

On 29th January 1819 Raffles established a post on this newly discovered island and immediately made contact with the local rulers. This proved to be Raffles’ strength, sensing an uneasy political context he offered what would have been a basic treaty establishing trade exclusivity and British protection of the area.

By 6th February 1819 Singapore had been established and Britain was in control. The treaty was announced in public, read in several languages in order to show inclusion of all people belonging to this multicultural trade centre. Raffles had secured an important port, leading to the city’s growth not only financially but culturally and socially, attracting people from all across the continent hoping to make money on the island. Modern Singapore was taking its tentative steps on the global stage. In the following years, Singapore would formally become a British colony with power transferred to Major William Farquhar as the Resident and Commandant of the new settlement. Raffles, although initially returning to Sumatra, would continue to exert his influence on Singapore throughout the years.


27/07/2024

Suspension of sales of sibutramine products

HSA Suspends Sales of Sibutramine Products with Immediate Effect

The Health Sciences Authority (HSA) is suspending the sales of sibutramine products in Singapore with effect from 11 Oct 2010, after consulting its Pharmacovigilance Advisory Committee (PVAC) and a panel of external experts in metabolic diseases and cardiology. This decision was made following a benefit-risk assessment of sibutramine, which concluded that the increased cardiovascular risk of sibutramine outweighed the modest weight loss seen in patients. The deliberations have taken into consideration the findings from the Sibutramine Cardiovascular Outcomes (SCOUT) study, the use of the product locally, and developments in other international jurisdictions.

Sibutramine is licensed for use in Singapore since 2001 as an adjunctive therapy to diet and exercise for obesity and for overweight patients with obesity-related risk factors such as Type 2 diabetes or disorders in lipid metabolism. It is marketed under four different brands in Singapore - Reductil®, Ectiva®, Reduxade® (all by Abbott) and Slenfig® (Apotheca Marketing).

The SCOUT study was a large study designed to evaluate the cardiovascular (CV) safety after the long-term use of sibutramine in patients who had a history of CV disease and/or type 2 Diabetes Mellitus (DM) with at least one CV-related risk factor such as high blood pressure and high lipid levels. Approximately 10,000 patients who were overweight and obese, aged 55 years and older were recruited in the study and treated up to six years. This study has shown a moderate increased risk of serious CV events associated with sibutramine use in patients with pre-existing CV disease.


Banned weight loss substance that increases heart attack, stroke risk found in coffee sachets
V-SHOU Premium Coffee has been found to contain sibutramine

A prescription-only weight loss medicine that has been banned in Singapore since 2010 has been detected in a coffee product sold on various local e-commerce platforms, the Singapore Food Agency (SFA) said on Wednesday (Jul 24). 

Consumers are advised not to purchase or consume V-SHOU Premium Coffee as it contains sibutramine, a substance that is known to increase the risk of heart attack and stroke. Other serious health consequences reported with sibutramine's use include heart problems, central nervous system disorders such as psychosis and hallucinations, and seizures.

Marketed as a weight-loss product, V-SHOU Premium Coffee made several claims, such as accelerated fat burning, enhanced metabolism, quicker slimming results, as well as soothing the digestive system and controlling appetite. White kidney bean extract and hoodia gordonii, which has been touted as an appetite suppressant, are among its listed ingredients. The product's packaging does not state where it was formulated and its country of origin is unknown.


Banned weight loss substance that increases risk of heart attack, stroke found in coffee premix
ChoCo Premix Coffee has been found to contain sibutramine

Sibutramine, a weight loss substance banned in Singapore, has been detected in a food product sold on various local e-commerce platforms, the Singapore Food Agency (SFA) said on Monday (Jul 15).

Consumers are advised not to purchase or consume ChoCo Premix Coffee, which lists chocolate and hoodia gordonii extract among its ingredients. Hoodia gordonii has been touted as an appetite suppressant. Marketed as a weight loss product, ChoCo Premix Coffee made several claims, including weight loss, avoidance of muscle loss, acceleration of fat burning, fat removal, reduction in hunger, improvements in constipation, repair muscle and increase muscle mass. While the product's packaging says it is "formulated in USA", its country of origin is unknown and not listed.

"SFA has worked with various online e-commerce platforms to remove the listings of the product and issued warnings to the respective sellers to stop selling the product with immediate effect," said the agency. Sibutramine is a prescription-only weight loss medicine that has been banned in Singapore since 2010, due to an increased risk of heart attack and stroke. Other serious health consequences reported with its use include central nervous system disorders, such as psychosis and hallucinations, and heart problems. Seizures have also been reported with sibutramine.


HSA issues warning for 3 products containing banned weight loss medicine, steroids
The Health Sciences Authority has warned members of the public not to purchase or consume "‘LORENXO DELICIOUS PURE CHOCOLATE SUPPLEMENT" and "MOFA COFFEE".

Members of the public have been warned by the Health Sciences Authority (HSA) against buying several products that were found to contain "potent medicinal ingredients".

The products contain substances including erectile dysfunction medicine tadalafil, steroids and sibutramine, a substance banned in Singapore because of an increased risk of heart attacks and strokes. The affected products are: "LORENXO DELICIOUS PURE CHOCOLATE SUPPLEMENT", "DND Rx9" and "MOFA COFFEE". Two consumers developed adverse effects after taking the products, HSA said in a media release.

"LORENXO DELICIOUS PURE CHOCOLATE SUPPLEMENT" and "MOFA COFFEE" were sold on local online e-commerce and social media platforms including Carousell, Qoo10, Shopee and Facebook, said HSA. The authority added that it has worked with the platform adminstrators to remove the affected listings. It has also alerted its Malaysian counterpart to "DND Rx9" and "MOFA COFFEE", which were purchased or sourced from Malaysia.


HSA warns against two 'slimming products' after consumers suffer adverse effects
The Health Sciences Authority has warned the public not to purchase or consume ENRU PLUS+ and HKT HERBA KURUS TRADISI

The Health Sciences Authority (HSA) has warned members of the public against buying four products that were found to contain “potent medicinal ingredients”. These ingredients included sibutramine, a weight loss substance banned in Singapore, as well as erectile dysfunction medicine tadalafil and steroids.

The affected products are ENRU PLUS+, HKT HERBA KURUS TRADISI, PILL HUA LUO CIN TAN and Spinach GINSENG HERB SUGAR. ENRU PLUS+ and HKT HERBA KURUS TRADISI were marketed online as slimming products and carried labels claiming that they contained natural ingredients. They caused adverse effects such as breathlessness and heart palpitations in three women, said HSA.

All four products were sold on local e-commerce platforms such as Shopee, Lazada, Carousell and Qoo10 by sellers based in Singapore and Malaysia. ENRU PLUS+ was also marketed on Facebook. HSA said it has worked with platform administrators to remove the affected listings and issued warnings to the respective sellers. It also alerted its Malaysian counterpart about these four products, which were sold in Malaysia or by Malaysia-based sellers.


3 people suffer adverse effects after taking slimming products containing banned substance
Magic Mocha, Thao Moc Ho Tro Giam Beo Cenly and Cynthia Beauty EazyS Instant Coffee Powder

Three people suffered adverse effects such as palpitations and nausea after taking slimming products that contained the banned substance sibutramine, the Health Sciences Authority (HSA) said on Wednesday (Nov 10).

The products are Magic Mocha, Thao Moc Ho Tro Giam Beo Cenly and Cynthia Beauty EazyS Instant Coffee Powder. They were sold on e-commerce sites like Carousell, Lazada, Shopee and Qoo10 and social media platforms like Facebook and Instagram. "They were marketed with misleading claims which included 'fast-acting', 'fat-burning', 'reduce fat storage' and 'accelerate the breakdown of stubborn fat'," said HSA.

The authority said it has issued warnings to the sellers and platform administrators have since removed the affected listings. HSA said it received three reports from consumers who experienced palpitations, nausea, extreme thirst, migraine or dizziness after taking the products. An analysis of the slimming products showed that they contained sibutramine (banned since 2010), which can cause serious adverse effects.


Four Products Found to Contain Banned Substance Sibutramine; One Consumer Had Adverse Effects

The Health Sciences Authority (HSA) is alerting members of the public not to purchase or consume four products marketed online as weight loss products. Contrary to the ingredients listed on the packaging, HSA’s analysis of these products revealed that they contained the banned substance, sibutramine, which can cause serious adverse effects in consumers.

The four products are:
  • ‘Flash Slim’
  • ‘Leedee Botanical Beverage Mix Pineapple Juice Powder with African Mango’
  • ‘Quinn S Amyera’
  • ‘Schocolite Double Chocolate Cookies Drink with Hoodia Gordinii Extract and L-Carnitine’

The products were sold on local e-commerce and social media platforms. HSA has worked with the platform administrators to promptly remove the affected listings and issued warnings to the respective sellers.


Sibutramine

Sibutramine was withdrawn from the U.S. market in October 2010. Sibutramine affects chemicals in the brain that affect weight maintenance. Sibutramine is used together with diet and exercise to treat obesity that may be related to diabetes, high cholesterol, or high blood pressure. Sibutramine may also be used for other purposes not listed in this medication guide.

Do not use sibutramine if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days. Serious, life threatening side effects can occur if you use sibutramine before the MAO inhibitor has cleared from your body. You should not take sibutramine if you are allergic to it, or if you have severe or uncontrolled high blood pressure, an eating disorder (anorexia or bulimia), if you are taking stimulant diet pills, or if you have a history of coronary artery disease, stroke, or heart disease.

Before taking sibutramine, tell your doctor if you have glaucoma, high blood pressure, liver or kidney disease, depression, underactive thyroid, seizures, a bleeding disorder, a history of gallstones, or if you are older than 65 or younger than 16. Tell your doctor about all prescription and over-the-counter medications you use, especially antidepressants, cold or allergy medication, narcotic pain medicine, or migraine headache medicines. Tell your doctor if you do not lose at least 4 pounds after taking the medication for 4 weeks along with a low calorie diet.


Sibutramine

Sibutramine is a norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity.

Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States.

In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.


Sibutramine

Sibutramine, formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries. It works as a serotonin–norepinephrine reuptake inhibitor similar to a tricyclic antidepressant. Until 2010, it was widely marketed and prescribed as an adjunct in the treatment of obesity along with diet and exercise.

It has been associated with increased cardiovascular diseases and strokes and has been withdrawn from the market in 2010 in several countries and regions including Australia, Canada, China, the European Union, Singapore, Hong Kong, India, Mexico, New Zealand, the Philippines, Thailand, the United Kingdom, and the United States. However, the drug remains available in some countries. Sibutramine was originally developed in 1988 by Boots in Nottingham, UK and manufactured and marketed by Abbott Laboratories and sold under a variety of brand names including Reductil, Meridia, Siredia, and Sibutrex before its withdrawal 2010 from most markets. It was classified as a Schedule IV controlled substance in the United States.

As of 2018, the FDA still found sibutramine in over 700 diet supplements marketed as "natural", "traditional" or "herbal remedies". Sibutramine has been used to produce appetite suppression for the purpose of attaining weight loss in the treatment of patients with obesity.

26/07/2024

Olympic Games Paris 2024


Singapore's Max Maeder wins kitefoiling bronze medal on Olympic debut
Maximilian Maeder celebrates after winning bronze at the Paris Olympics

Singaporean kitefoiler Maximilian Maeder has delivered a birthday present to the nation as he clinched a bronze medal at the Paris Olympics on Friday (Aug 9).

At the Marseille Marina today (Aug 9), four riders — Maeder, Slovenia's Toni Vodisek, Austria's Valentin Bontus and Italy's Riccardo Pianosi — raced for podium finishes.

The final, which started on Thursday, was postponed due to wind conditions. He is Singapore's youngest Olympic medalist, at 17 years old.


Australian swim coach Brett Hawke calls out Chinese Olympian Pan Zhanle's world record swim as 'not humanly possible'
Olympic Chinese swimmer Pan Zhanle’s stunning world record achievement in the men’s 100m freestyle final has been called out by a renowned Australian swim coach, who argues the feat was “not humanly possible”

Australian swim coach Brett Hawke has shared his scepticism after Chinese Olympic swimmer Pan Zhanle smashed his own world record in Thursday's 100m freestyle final. The 19-year-old stunned spectators when he beat Australian competitor Kyle Chalmers, 26, by 1.08 seconds – breaking his own world record by finishing in 46.40 seconds.

Hawke took to Instagram in the wake of the massive achievement, arguing it was just “not humanly possible”. The 49-year-old, whose career has spanned 30 years and who was an Olympic sprint freestyler himself, posted a video saying he was “angry” at the race for a number of reasons. “Look, my friends are the fastest swimmers in history from Rowdy Gaines to Alex Popov to Gary Hall Jr, Anthony Irvin, all the way up to King Kyle Chalmers. I know these people intimately, I’ve studied them for 30 years,” he said.

“I’ve studied this sport. I’ve studied speed. I understand it. I’m an expert in it, that’s what I do, okay. He argued it was not possible to win a 100-metre freestyle by a body length on the field – saying “you just don’t do it”. “It is not humanly possible to beat that field by a body length,” he said.



Chinese swimmer Pan Zhanle's historic win at Olympics 'doesn't make any sense'
Swim coach and former Olympic swimmer Brett Hawke has analysed Chinese swimmer Pan Zhanle’s win at the Paris Olympics saying the result “makes no sense”

Top Aussie swim coach Brett Hawke has questioned Chinese swimmer Pan Zhanle's historic win at the Paris Olympic Games, arguing it "doesn't make any sense". Pan shocked the swimming world when he finished at a record time of 46.40 seconds in the men's 100m freestyle final on Thursday, beating Australian sprint swimmer Kyle Chalmers. The 19-year-old Chinese athlete, who beat his own world record time, touched the wall 1.08 seconds faster than Chalmers and 1.09 seconds in front of Romania's David Popovici.

The magnitude of Pan's final win has come under scrutiny from critics as he finished almost a body length in front of his competitors in what is historically known to be a close race. The criticism comes amid developments in doping accusations against Chinese athletes. Pan has never tested positive for drugs. Speaking to Sky News Australia host Peter Stefanovic on Friday, Hawke, a former Olympic swimmer, said he has "questions" about Pan's 100m freestyle final achievement. "Mate, I think we're all stunned. Everybody watching that swim yesterday was stunned," he told Stefanovic.

Hawke, a five-time Olympian who has coached world swimming greats including Brazil's César Cielo, claimed there were "multiple reasons" why Pan's win "doesn't make any sense". The 49-year-old pointed to Chalmers' achievements in the men's 100m freestyle event in the past, including a first and second placings at previous Olympic Games. "He (Chalmers) has finished second here at this one, but he's got obliterated here by the Chinese swimmer and it just doesn't make any sense for many reasons," Hawke claimed.


Opening Ceremony of the Centenary Olympics Games in Paris on 26 Jul 2024

The 2024 Summer Olympics (Jeux olympiques d'été de 2024), officially the Games of the XXXIII Olympiad (Jeux de la XXXIIIe Olympiade) and officially branded as Paris 2024, is an ongoing international multi-sport event taking place from 24 July to 11 August 2024 in France, with the Opening Ceremony taking place on 26 July. Paris is the main host city, with events held at 16 other cities spread across Metropolitan France, plus one subsite in Tahiti, French Polynesia.


THE CENTENARY OF THE PARIS 1924 OLYMPIC GAMES

In 2024, Paris will become just the second city to host the Olympic Summer Games three times after London (which staged the 1908, 1948 and 2012 Olympic Games).

The City of Lights first hosted the Olympic Games in 1900, four years after the multi-sport event was resurrected in Athens after being banned by Roman Emperor Theodosius I some 1,500 years earlier. No opening or closing ceremonies were held at the 1900 Olympics, which featured female competitors for the first time in Olympic history, as well as other unique events including ballooning, underwater swimming and cricket. Paris hosted the Summer Olympics again in 1924, becoming the first city to host the Olympics twice. While the Opening Ceremony of the 1924 Olympics was held on 5 July, some competitions began on 4 May, with the Closing Ceremony held on 27 July.

100 years later, on 26 July 2024, Paris will officially welcome the world to the Olympic Games for a third time, while these Olympics will be the sixth held in France (in addition to the three Summer Olympics mentioned above, France has also staged the Winter Olympics on three occasions: Chamonix 1924, Grenoble 1968 and Albertville ‘92).


Paris Olympics 2024 - Things to know
"Olympic Flame" Paris Olympics 2024

Here are some interesting details about the mega event:
  • The Paris Olympics 2024 will take place between 26th July and 11th August next year. The Paralympic Games will be held from 28th August to 8th September.
  • The Paris Olympics 2024 will be held in the city exactly a hundred years after it hosted the event in 1924.
  • The opening ceremony will not take place in the stadium for the very first time. It will be held on the River Seine.
  • The Olympics 2024 will have a total of 32 sports played, with a total of 329 medal events.
  • Aquatics has the highest number of medals with a total of 49 events throughout marathon swimming, swimming, water polo, artistic swimming, and diving. Athletics follows next with 48 events.
  • 10,500 athletes are expected to be in attendance for the event next year. The final competitor count will be confirmed after the Olympic Qualifier Series concludes.
  • The 2024 edition of the Olympics will have a new sport, namely breaking. This is a dance-based sport where there will be competitions for both men and women. 16 B-Boys and 16 B-Girls will go head-to-head in solo contests.
  • The Olympics 2024 will have 35 venues, with 14 sites to host 24 Olympics sports within only 10 kilometres of the Olympic Village.
  • Some events will take place at famous venues in Paris. For instance, beach volleyball will take place at the Champ de Mars beneath the Eiffel tower. Urban sports will take place at La Concorde and fencing and taekwondo competitions will be held at the Grand Palais. The Marathon will begin at the Hotel De Ville.
  • The Olympics will also cover other regions in France. The football tournament will cover Nantes, Bordeaux, Saint-Etienne, Lyon, Marseille, and Nice. Sailing will also take place in Marseille, while Lille will host some team sports competitions.
  • The Olympic Games will also take place in the French territory of Tahiti for the very first time. The surfing contest will be held on the famous Teahupoo wave of the island.
  • Sailing will have two new categories at the Paris Olympics 2024, namely IQFoil or windsurfing and Kite surf or formula kite.
  • A new event will be introduced in the canoe category which is called Extreme slalom. There will be four athletes tipping off the ramp simultaneously, with the winner being the one reaching the bottom of the course first. Men and women will have an event each in this category.
  • The Olympic Games will also witness three new mixed events. These include the waking mixed relay for 35 kilometres (athletics), Skeet mixed team event (shooting), and mixed Dinghy (sailing).
  • Sport climbing, which was introduced in 2021 at the 2020 Olympic Games in Tokyo, will have a change in its format. There will be two medal events for both men and women. One will be a combined bouldering and lead event and one will be a speed climbing competition.
  • Around 10 million tickets are expected to be available for sale for the next Olympics 2024. Prices are expected to start from 24 Euros while the lowest prices will be around15 Euros for the Paralympic sports.
  • The format of the Modern Pentathlon will also change, covering 90 minutes. It will start with riding, followed by fencing bonus rounds and swimming. The final round will be the laser run that combines running and shooting. Every sport will have 5-15-minute breaks in between.
  • The Olympic Games will have an IOC Refugee Team. The first such team participated in the 2016 edition of the event in Rio.
  • The Olympic Flame will arrive in the country after crossing the Mediterranean Sea. It will mark the celebrations from 8th May, 2024 onwards in Marseille. This will cover four months throughout France. The opening ceremony will start after the Olympic Torch relay ends.
  • There will be 762 sessions for the events, with 19 days of competitions. The first official day is 27th July, 2024, which will have the time trial for men and women, along with events for cycling, rugby, fencing, judo, diving, skateboarding, swimming, and shooting.
  • All finals for the athletics and swimming events will be held in the evenings from 19:00 and 20:30 (the last day will have a timing of 18:30) onwards respectively. The middle period of 3rd to 4th August will have medal events for judo, table tennis, fencing, archery, athletics, cycling, equestrian, golf, artistic gymnastics, rowing, swimming, and badminton. The last day, i.e. 11th August, will have the track cycling, weightlifting, and wrestling events for women. The women’s basketball final is also scheduled for the final day. The Closing Ceremony will take place thereafter.


THE OLYMPIC GAMES OF PARIS 2024

The Paris 2024 Olympic (16 Jul to 11 Aug 2024) and Paralympic Games (28 Aug to 8 Sep 2024) will be the biggest event ever organised in France. The Olympic Games will take place from 26 July to 11 August 2024, when Paris will become the centre of the world—the world of sport, and so much more. The Games are a popular, multicultural festival shared by so many people around the planet and represent a new adventure for France unlike anything it has experienced before.

OLYMPIC GAMES IN A FEW FIGURES:
  • Billions of television viewers worldwide
  • 350,000 hours of TV broadcast
  • Millions of spectators
  • 35 venues
  • 10,500 athletes
  • 20,000 accredited journalists
  • 45,000 volunteers
  • +600,000 meals served at the Athletes’ Village every day

PARIS 2024 OLYMPIC GAMES KEY FIGURES:
  • The XXXIII Olympiad
  • 26 July to 11 August 2024
  • 19 days of competition (handball, football and rugby take place from 24 July)
  • 329 events
  • Athletes from over 200 NOCs and the IOC Refugee Olympic Team
  • 32 sports (including the 4 additional sports)
  • 754 sessions (competitions and ceremonies)
10,500 athletes


2024 Summer Olympics
Emblem of the 2024 Summer Olympics Games from 26 Jul to 11 Aug 2024

The 2024 Summer Olympics (French: Jeux olympiques d'été de 2024), officially the Games of the XXXIII Olympiad (French: Jeux de la XXXIIIe Olympiade) and officially branded as Paris 2024, is an upcoming international multi-sport event scheduled to take place from 26 July (the date of the opening ceremony) to 11 August 2024 in France, with some competitions starting on 24 July. Paris is the main host city, with events held at 16 other cities spread across Metropolitan France, plus one subsite in Tahiti—an island within the French overseas country and overseas collectivity of French Polynesia.

Paris was awarded the Games at the 131st IOC Session in Lima, Peru, on 13 September 2017. After multiple withdrawals that left only Paris and Los Angeles in contention, the International Olympic Committee (IOC) approved a process to concurrently award the 2024 and 2028 Summer Olympics to the two remaining candidate cities; both of the bids were praised for high technical plans and innovative ways to use a record-breaking number of existing and temporary facilities. Having previously hosted in 1900 and 1924, Paris will become the second city ever to host the Summer Olympics three times (after London which hosted the 1908, 1948 and 2012 Games).

Paris 2024 will mark the centenary of Paris 1924 and Chamonix 1924 (which in turn marks the centenary of the Winter Olympics), will be the sixth Olympic Games hosted by France (three Summer Olympics and three Winter Olympics) and the first French Olympics since the 1992 Winter Games in Albertville. The Summer Games will return to the traditional four-year Olympiad cycle, after the 2020 Tokyo Olympics were postponed until 2021 because of the COVID-19 pandemic. Paris 2024 will feature the debut of breakdancing as an Olympic event and could be the final Olympic Games held during the IOC presidency of Thomas Bach. The 2024 Games are expected to cost €9 billion.


Singapore at the 2024 Summer Olympics
23 athletes will be representing Singapore at the Games from 26 Jul to 11 Aug 2024

Singapore is scheduled to compete at the 2024 Summer Olympics in Paris from 26 July to 11 August 2024. It will be the nation's eighteenth appearance at the Summer Olympics since its debut at the 1948 Games.

Singapore has competed in every edition since except 1964 in Tokyo, as part of Malaysia team, and 1980 in Moscow, because of its support for the United States boycott.

On 16 April, former Olympian and sailor Tan Wearn Haw have been selected as the Chef De Mission of the Singapore delegation in Paris. In all, 23 athletes will be representing Singapore at the Games with Shanti Pereira and Ryan Lo selected as the flag bearers.


Singapore at the Olympics

The country has won five Olympic medals, the first was at the 1960 Summer Olympics, the second at the 2008 Summer Olympics and the third and fourth at the 2012 Summer Olympics. At the 2016 Summer Olympics Singapore won their first ever gold medal and the fifth overall.

Singapore's first Olympic medal was won by Tan Howe Liang, who won silver in lightweight weightlifting in 1960 Summer Olympics. The first and to date only Olympic gold medal was won by Joseph Schooling in the men's 100 metre butterfly at the 2016 Summer Olympics. In table tennis, Jing Junhong, Li Jiawei and Yu Mengyu came close to winning medals by finishing in fourth place for the women's singles events at the 2000 Sydney Olympics, 2004 Athens Olympics and 2020 Tokyo Olympics respectively.

In the 2016 Rio Olympics, Olympic swimmer Joseph Schooling won a gold medal in the Men's 100 metre butterfly in an Olympics record of 50.39 seconds, becoming the first gold Olympic medallist of Singapore. This was also the first gold medal by a Southeast Asian male swimmer and the first Olympic gold that Singapore achieved. During the 2020 Summer Olympics held in Tokyo, Japan, Singapore sent 23 athletes to the Games but did not manage to win any medals


Singapore in the Olympics


Singapore’s past Olympic medallists

Singapore made its Olympic debut as a British colony at London 1948 with its sole representative, fireman Lloyd Valberg, who was the late grand uncle of Olympic champion Joseph Schooling. He finished joint-14th out of 27 high jumpers with a 1.8m leap.

Since then, the Republic’s athletes have competed in every edition of the Games, except in Moscow 1980 when Singapore joined a United States-led boycott.

The Straits Times looks at the medallists through the years:
  • Tan Howe Liang, weightlifting (1960)
  • Feng Tianwei, Li Jiawei, and Wang Yuegu, table tennis (2008, 2012)
  • Feng Tianwei, table tennis (2012)
  • Joseph Schooling, swimming (2016)
  • Max Maeder, kitefoiling (2024)


Paralympic Games Medals

Singapore began their participation in the Paralympic Games when a squad was sent to the 1988 Summer Paralympics held in Seoul, South Korea. Despite winning no medals in the 1988 Summer Games, Singapore continued to send teams to the Summer Paralympics.[1] At the 2008 Summer Paralympics, Singapore sent six athletes and came home with four medals. The 2008 Games was the first time Singapore has won a medal in any Paralympic competition